ANSWER: "D" All of these will stand out to this employer:
Typos - always a bad idea - and know matter what, typos are a sign of inattentive work (did you catch the pun above?)
The appropriateness of your degree. YES, an employer cares if you have an appropriate degree - but it may surprise you what that means - keep reading.
Your professionally related experience. YES, YES and Yes. - but why?