Center for Water and the Environment

David Stachura

Assistant Professor of Civil Engineering

Research Interests 

Dr. Stachura and his students primarily study the molecular control of blood cell development.  They are interested in how hematopoietic stem cells (HSCs) proliferate and differentiate into progenitors and mature functional blood/immune cells.  While they are interested in how blood cells are made and differentiate, they also have an interest in the dysregulation of these cells and their role in hematopoietic disease.

They utilize a novel model system that is extremely genetic amenable; the zebrafish (Danio rerio).  While our primary focus is using the zebrafish to understand and model human development and disease, they also are interested in the evolution and function of the teleost immune system, a huge focus of aquaculture.  Another interest is using the zebrafish to understand water quality and substances/chemicals that affect metabolism, which affects many different types of tissue-specific stem cells.  In essence, they are interested in using the zebrafish to understand and model molecular changes that may occur after exposure to these agents.  They are always looking for like-minded collaborators; feel free to contact us to discuss possible projects. 

Research Projects

Zebrafish stem and progenitor cells and their dysregulation in leukemogenesis (1 K01 DK087814-01A1) funded by National Institute of Health, National Institute of Diabetes and Digestive and Kidney Diseases.

Research Areas

Human Health, Water, Other